Which of the following has the potential of undergoing Spontaneous malignant transformation _____________?
Correct answer: C. Paget's disease of bone
- A. Osteomalacia
- B. Albright's syndrome
- C. Paget's disease of bone
- D. Osteogenesis imperfecta
Explanation
Paget disease of bone can rarely undergo sarcomatous transformation, classically to osteosarcoma or fibrosarcoma. Fibrous dysplasia can also transform exceptionally rarely, but Paget disease is the standard answer in this comparison.
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