In a middle - aged man the radiograph shows cotton-wool appearance and blood investigation reveal an elevated alkaline phosphatase levels. The tentative diagnosis is____________?
Correct answer: A. Paget's disease
- A. Paget's disease
- B. Cherubism
- C. Fibrous dysplasia
- D. Osteogenesis imperfecta
Explanation
A cotton-wool radiographic pattern combined with raised alkaline phosphatase strongly indicates Paget disease, reflecting disorganized high-turnover bone remodeling. The other listed disorders do not characteristically produce this combination.
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