Asked in ETEA MDCAT 2010 2010Moderate

Which of the following groups is considered to have a deactivating effect during aromatic substitution?

Correct answer: D. -CN

  • A. -OH
  • B. -OR
  • C. -NH2
  • D. -CN

Explanation

-CN (Cyano group) is a deactivating group. It withdraws electron density from the ring through the inductive effect, reducing the reactivity of the system.

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About Benzene and Aromatic Compounds

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