Asked in ETEA MDCAT 2010 2010Moderate

Which of the following functional groups in NOT ortho para directing and activating?

Correct answer: C. COR

  • A. R
  • B. OH
  • C. COR
  • D. NH2

Explanation

The acyl group (COR) is not ortho para directing and activating. It is a deactivating group due to the presence of the carbonyl group (C=O), which withdraws electron density from the ring. As a result, the acyl group directs substitution reactions away from the ortho and para positions.

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