Which of the following antibiotics is most frequently associated with pseudomembranous colitis ?

Correct answer: C. Clindamycin

  • A. Ampicillin
  • B. Penicillin
  • C. Clindamycin
  • D. Cephalosporin

Explanation

Clindamycin is classically associated with Clostridioides difficile overgrowth and pseudomembranous colitis because it markedly disrupts normal intestinal flora. Other antibiotics can also cause it, but clindamycin is the classic exam association.

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