Moderate

Which kind of therapy was given in 1990 to a four­ year­ girl with Adenosine Deaminase (ADA) enzyme deficiency?

Correct answer: A. Gene therapy

  • A. Gene therapy
  • B. Chemotherapy
  • C. Immunotherapy
  • D. Radiation therapy

Explanation

Gene therapy is a technique of genetic engineering which involves the replacement of a faulty/disease-causing gene by a normal healthy functional gene. The first clinical ex-vivo gene therapy was given in 1990 to a 4­-year old girl with adenosine deaminase (ADA) enzyme deficiency. This enzyme is very important for the immune system to function and the deficiency of this enzyme can lead to severe combined immune deficiency (SCID).

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Biotechnology in health care applies biological organisms, cells or enzymes to diagnose and treat disease. The subject includes recombinant DNA, genetically engineered insulin, vaccines, antibiotics, monoclonal antibodies, gene therapy and techniques such as polymerase chain reaction, while distinguishing therapeutic applications from agricultural and industrial biotechnology.

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