Which feature best distinguishes apoptosis from necrosis?
Correct answer: C. Cell shrinkage with formation of apoptotic bodies
- A. Cell swelling with membrane rupture
- B. Marked neutrophil accumulation
- C. Cell shrinkage with formation of apoptotic bodies
- D. Extensive inflammation around dead cells
Explanation
Apoptosis involves programmed cell shrinkage, nuclear fragmentation and formation of membrane-bound apoptotic bodies, usually without inflammation. Cell swelling, membrane rupture and inflammation are typical features of necrosis.
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Covers the causes and mechanisms of disease, cellular injury, inflammation, healing, circulatory disturbances, neoplasia and disorders of major organs. It also includes gross and microscopic pathological changes, specimen interpretation and the distinction between aetiology, pathogenesis, clinical signs and lesions.
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