What is the product when acid anhydride is reacted with amine?
Correct answer: B. Amide
- A. Nitrile
- B. Amide
- C. Ammonia
- D. Acid nitrile
Explanation
This is a nucleophilic acyl substitution reaction. The amine acts as a nucleophile and attacks one of the carbonyl carbons of the anhydride, leading to the formation of an amide and a carboxylate salt as products.
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About Carboxylic Acid Derivatives
Carboxylic acid derivatives include acid halides, acid anhydrides, esters and amides, formed by replacing the hydroxyl group of a carboxylic acid. Their nomenclature, structures, preparation, hydrolysis and relative reactivity are linked through nucleophilic acyl substitution, which differs from the nucleophilic addition reactions of aldehydes and ketones.
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