What happens if we react a carboxylic acid with an acyl chloride?
Correct answer: A. It forms an acid anhydride
- A. It forms an acid anhydride
- B. It forms an acyl halide
- C. It does not react due to resonance
- D. It does not react due to bad leaving group
Explanation
When a carboxylic acid reacts with an acyl chloride, it forms an acid anhydride through the elimination of HCl. The general reaction can be represented as:RCOCl + R'COOH → RCOOCOR' + HCl
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About Carboxylic Acid Derivatives
Carboxylic acid derivatives include acid halides, acid anhydrides, esters and amides, formed by replacing the hydroxyl group of a carboxylic acid. Their nomenclature, structures, preparation, hydrolysis and relative reactivity are linked through nucleophilic acyl substitution, which differs from the nucleophilic addition reactions of aldehydes and ketones.
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