What base is responsible for hot spots of spontaneous point mutations?
Correct answer: B. 5-methylcytosine
- A. 5-bromouracil
- B. 5-methylcytosine
- C. Guanine
- D. Adenine
Explanation
Spontaneous deamination of 5-methylcytosine creates thymine (C→ T), making CpG sites mutation "hot spots."
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Chromosomes are DNA-protein structures that carry genes and become visible during cell division. Coverage includes chromatin, centromeres, sister chromatids, homologous chromosomes, chromosome number, and the distinction between diploid and haploid cells, with links to DNA replication, mitosis and meiosis.
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