Moderate

During translation initiation in prokaryotes, a GTP molecule is needed in the:

Correct answer: D. Association of 50S subunit of ribosome with initiation complex

  • A. Formation of formyl-­met­-tRNA
  • B. Binding of 30S subunit of ribosome with mRNA
  • C. Association of 30S-mRNA with formyl­-met-tRNA
  • D. Association of 50S subunit of ribosome with initiation complex

Explanation

In prokaryotic translation initiation, a GTP molecule is required for the step where the 50S ribosomal subunit joins the 30S initiation complex to form the complete 70S initiation complex. This GTP is hydrolyzed by initiation factor IF2 to facilitate the joining of the 50S subunit.

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