Asked in PMC Practice Test 35 (2021) 2021Moderate

The substrate binds to a specific region on the enzyme called?

Correct answer: B. Active site

  • A. Key
  • B. Active site
  • C. Hyperactive site
  • D. None of these options are correct

Explanation

The substrate binds to a specific region on the enzyme called the active site. The active site is a pocket or crevice on the surface of the enzyme that is complementary to the shape of the substrate. The substrate binds to the active site through a series of weak interactions, such as hydrogen bonds and van der Waals forces. Once the substrate is bound to the active site, the enzyme can catalyze the reaction.

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About Mode of Enzyme Action

Enzyme action depends on the active site forming a temporary enzyme substrate complex, then converting substrate into products with lower activation energy. The lock and key and induced fit models explain specificity and binding, while cofactors and changes in enzyme shape can affect catalysis.

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