The One genome-one enzyme hypothesis was postulated by:
Correct answer: A. Beadle and Tatum
- A. Beadle and Tatum
- B. R. Franklin
- C. Hershey and Chase
- D. A. Garrod
Explanation
In 1948, Beadle and Tatum proposed the one gene oneenzyme hypothesis which states that a gene controls the metabolic machinery of the organism through the synthesis of an enzyme. This laid the foundation of biochemical genetics. Beadle and Tatum were awarded the Nobel Prize in 1958. This one gene-one enzyme theory has now been changed to the one gene-one polypeptide hypothesis as proposed by Yanofsky. This hypothesis suggests that one gene synthesizes one polypeptide and many polypeptides form one enzyme.
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About Chromosomes
Chromosomes are DNA-protein structures that carry genes and become visible during cell division. Coverage includes chromatin, centromeres, sister chromatids, homologous chromosomes, chromosome number, and the distinction between diploid and haploid cells, with links to DNA replication, mitosis and meiosis.
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