Very hard

The Michaelis constant (Km) represents

Correct answer: B. Substrate concentration at half Vmax

  • A. Maximum reaction velocity
  • B. Substrate concentration at half Vmax
  • C. Enzyme concentration
  • D. Inhibitor concentration

Explanation

Km is the substrate concentration at which the reaction velocity is half of Vmax. It indicates enzyme-substrate affinity.

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About Enzyme Inhibitors

Enzyme inhibitors reduce reaction rate by interfering with enzyme-substrate interaction or catalytic activity. Coverage includes reversible competitive, non-competitive and uncompetitive inhibition, the effects of inhibitor concentration on reaction rate, and why competitive inhibition can be reduced by increasing substrate concentration.

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