Reversible inhibitors differ from irreversible inhibitors because they:

Correct answer: B. Bind temporarily and can be removed

  • A. Bind permanently and cannot be removed
  • B. Bind temporarily and can be removed
  • C. Permanently inactivate the enzyme
  • D. Change enzyme structure permanently

Explanation

A reversible inhibitor binds through weak interactions and detaches again, so activity returns when it is removed or outcompeted, which is how competitive and non competitive inhibitors behave. An irreversible inhibitor forms a covalent bond, as heavy metal ions and nerve gases do, and the enzyme is destroyed for good. The other three options all describe the irreversible case.

This question appeared on the UHS MDCAT 2025 paper, which you can sit online with every answer explained.

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About Enzyme Inhibitors

Enzyme inhibitors reduce reaction rate by interfering with enzyme-substrate interaction or catalytic activity. Coverage includes reversible competitive, non-competitive and uncompetitive inhibition, the effects of inhibitor concentration on reaction rate, and why competitive inhibition can be reduced by increasing substrate concentration.

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