Competitive inhibitors
Correct answer: C. Bind to active site
- A. Bind to allosteric site
- B. Cannot be overcome by increasing substrate
- C. Bind to active site
- D. Change Vmax but not Km
Explanation
Competitive inhibitors bind to the active site, competing with substrate. They can be overcome by increasing substrate concentration.
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About Enzyme Inhibitors
Enzyme inhibitors reduce reaction rate by interfering with enzyme-substrate interaction or catalytic activity. Coverage includes reversible competitive, non-competitive and uncompetitive inhibition, the effects of inhibitor concentration on reaction rate, and why competitive inhibition can be reduced by increasing substrate concentration.
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