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The high specificity of an enzyme for its substrate is due to

Correct answer: A. the shape and chemistry of its active site

  • A. the shape and chemistry of its active site
  • B. its molar mass
  • C. the temperature of the reaction
  • D. the concentration of the substrate

Explanation

Only a substrate whose shape and charge distribution complement the active site can bind, which is why sucrase acts on sucrose but not on the closely related maltose. The induced fit model refines this picture by allowing the site to mould itself around the substrate as binding occurs. Specificity is a structural property and is unaffected by temperature or concentration.

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About Enzymes as Biocatalysts

Enzymes are protein or RNA biocatalysts that lower activation energy without being consumed, and their active sites bind specific substrates. The topic covers the lock and key and induced fit models, effects of temperature, pH and substrate concentration, cofactors, enzyme specificity, and competitive versus non-competitive inhibition.

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