The half-life of a drug is best defined as the time required for the drug concentration in the blood to:
Correct answer: C. Fall to one half of its original level
- A. Reach its maximum therapeutic level
- B. Begin producing its first therapeutic effect
- C. Fall to one half of its original level
- D. Become completely removed from the body
Explanation
Half-life is the time needed for the plasma concentration of a drug to decrease by 50 percent. It does not mean that the entire drug is removed or that the therapeutic effect has ended.
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About Principles of Pharmacology
Pharmacology examines drug sources, names, dosage forms, mechanisms of action, absorption, distribution, metabolism and excretion. Questions cover pharmacokinetics versus pharmacodynamics, therapeutic effects, adverse reactions, contraindications, drug interactions, tolerance, dependence and the safety responsibilities of the nurse.
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