A patient with low serum albumin receives a highly protein-bound drug. Which effect should the nurse anticipate?
Correct answer: B. More free drug and increased toxicity risk
- A. Less free drug and reduced drug action
- B. More free drug and increased toxicity risk
- C. Slower absorption and delayed drug action
- D. Faster excretion and shorter drug action
Explanation
Albumin binds many drugs in the blood and limits the amount that is pharmacologically active. Low albumin can increase the free drug concentration and raise the risk of adverse or toxic effects.
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About Principles of Pharmacology
Pharmacology examines drug sources, names, dosage forms, mechanisms of action, absorption, distribution, metabolism and excretion. Questions cover pharmacokinetics versus pharmacodynamics, therapeutic effects, adverse reactions, contraindications, drug interactions, tolerance, dependence and the safety responsibilities of the nurse.
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