Sickle cell anemia is caused due to change of glutamic acid to:
Correct answer: C. Valine
- A. Histidine
- B. Leucine
- C. Valine
- D. Proline
Explanation
Sickle cell anemia is caused by a specific point mutation in the gene that encodes the beta-globin subunit of hemoglobin. In this mutation, the amino acid glutamic acid is substituted with valine at position 6 of the beta-globin chain. So, the correct answer is that in sickle cell anemia, glutamic acid is changed to valine.
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