Sickle cell anemia is a type of
Correct answer: D. Base Substitution
- A. Insertion
- B. Transposition
- C. Deletion
- D. Base Substitution
Explanation
In Sickle cell anemia, the gene for beta-globin is mutated. As a result, the amino acid valine is replaced by glutamic acid and the RBC adopts a sickle shape. Since it is a type of base substitution therefore opt D is the right choice here.
This question appeared on the UHS MDCAT 2014 paper, which you can sit online with every answer explained.
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DNA structure includes nucleotides made of deoxyribose, phosphate and nitrogenous bases, arranged in two antiparallel polynucleotide strands. Questions cover the double helix, phosphodiester and hydrogen bonds, complementary base pairing between adenine and thymine and between guanine and cytosine, and the significance of major and minor grooves.
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