Sickle cell anaemia results from:
Correct answer: C. Single amino acid substitution in the haemoglobin molecule
- A. Reduction in oxygen-carrying capacity of haemoglobin
- B. Linkage between the polypeptide chains in the haemoglobin molecule
- C. Single amino acid substitution in the haemoglobin molecule
- D. Viral infections of RNA viruses
Explanation
Sickle cell anemia is caused by a genetic mutation in the HBB gene, which provides instructions for making hemoglobin, the protein in red blood cells that carries oxygen throughout the body. This mutation leads to the production of an abnormal form of hemoglobin called hemoglobin S (HbS).
Last updated
About Chromosomes
Chromosomes are DNA-protein structures that carry genes and become visible during cell division. Coverage includes chromatin, centromeres, sister chromatids, homologous chromosomes, chromosome number, and the distinction between diploid and haploid cells, with links to DNA replication, mitosis and meiosis.
Practise Cell Structure and Function
2,478 free Cell Structure and Function MCQs from Biology, each with the correct answer and an explanation. Unlimited attempts, no account needed.
Exams that ask Biology questions like this
Biology is on 6 papers prepared for on TestUstad, and all of them draw the same bank, so this question is worth knowing for every one of them.
Related questions
1000-2000 Okazaki fragment:
200 nucleotide + 8 histones:
2n= 16 in a primary spermatocyte, which is in the metaphase of first meiotic division. What shall be the total number of chromatids in each of the secondary spermatocytes?
A 10 nucleotide sequence i.e., RNA primer is constructed by:
A cell contains 8 chromosomes in its diploid state.When this cell undergoes meiosis, its daughter cells would contain: