Asked in UHS MDCAT 2016 2016Moderate

Restriction endonucleases cleave the _ of duplex DNA.

Correct answer: C. Phosphodiester bond

  • A. Nitrogenous base
  • B. Base sugar
  • C. Phosphodiester bond
  • D. Hydrogen bond

Explanation

The restriction endonucleases cuts the two strands of the double helix at specific point in the sugar phosphate backbone of DNA, it breaks phosphodiester bonds between the phosphate and the pentose sugar.

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