Okazaki fragments are connected together through action of_________________?
Correct answer: D. Ligase
- A. Primase
- B. Polymerase
- C. Helicase
- D. Ligase
Explanation
DNA ligase joins Okazaki fragments on the lagging strand by sealing breaks in the sugar-phosphate backbone and forming phosphodiester bonds. Primase makes RNA primers, polymerase adds nucleotides, and helicase separates the DNA strands. Students often choose polymerase because it synthesises DNA, but it does not join the completed fragments together.
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