Purines and pyrimidines are in equal ration in DNA. It was indicated by_______________?
Correct answer: B. Chargaff
- A. F.Miescher
- B. Chargaff
- C. Watson & Crick
- D. Harshay & Chase
Explanation
Chargaff showed that DNA contains approximately equal amounts of purines and pyrimidines because adenine pairs with thymine and guanine pairs with cytosine. The likely alternative is Watson and Crick, who used such findings to propose the double-helix structure but did not make the original base-composition observation.
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About Structure of DNA
DNA structure includes nucleotides made of deoxyribose, phosphate and nitrogenous bases, arranged in two antiparallel polynucleotide strands. Questions cover the double helix, phosphodiester and hydrogen bonds, complementary base pairing between adenine and thymine and between guanine and cytosine, and the significance of major and minor grooves.
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