Lidocaine produces its antiarrhythmic effects by_____________?
Correct answer: B. Decreasing cardiac excitability
- A. Increasing A-V conduction
- B. Decreasing cardiac excitability
- C. Increasing cardiac conduction velocity
- D. Increasing spontaneous pacemaker activity
Explanation
Lidocaine blocks fast sodium channels in cardiac tissue, reducing abnormal automaticity and cardiac excitability, particularly in ventricular myocardium. It therefore does not increase conduction velocity, AV conduction or pacemaker activity.
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