In a tissue section, a granulomatous response to a foreign body is most likely to contain:
Correct answer: D. Multinucleated foreign-body giant cells
- A. Sheets of keratinized epithelium
- B. Only circulating erythrocytes
- C. Mature adipocytes without inflammation
- D. Multinucleated foreign-body giant cells
Explanation
Foreign-body granulomas commonly contain macrophages that fuse to form multinucleated foreign-body giant cells around material too large to phagocytose. The other choices do not represent the typical cellular response to persistent foreign material.
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Covers the causes and mechanisms of disease, cellular injury, inflammation, healing, circulatory disturbances, neoplasia and disorders of major organs. It also includes gross and microscopic pathological changes, specimen interpretation and the distinction between aetiology, pathogenesis, clinical signs and lesions.
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