If the father of a baby is hemophilic and the mother is a carrier then the chances of the baby inheriting the disease will be:

Correct answer: B. 50%

  • A. 0%
  • B. 50%
  • C. 75%
  • D. 100%

Explanation

If the father has hemophilia and the mother is a carrier, there is a 50% chance that the baby will inherit the disease. Haemophilia is an X-linked genetic disorder, which means it is passed down on the X chromosome. The baby has a 50% chance of inheriting the affected X chromosome from the carrier mother.

This question appeared on the ETEA MDCAT 2010 paper, which you can sit online with every answer explained.

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About X-linked Recessive Inheritance

X-linked recessive inheritance involves genes on the X chromosome, so males express a recessive allele with no corresponding allele on their single X chromosome, while females may be carriers. Pedigrees cover haemophilia and red-green colour blindness, including carrier mothers, affected sons and the absence of father-to-son transmission.

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