Events associated with lysosomal disorders are mentioned below. Arrange them in a sequence with respect to their occurrence: i. Mutation ii. Storage diseases iii. Accumulation of substances within the cells iv. Deficiency of lysosomal enzymes v. Metabolic sluggishness
Correct answer: B. i, iv, v, iii, ii
- A. i, ii, iii, iv, v
- B. i, iv, v, iii, ii
- C. v, iv, iii, ii, i
- D. ii, iii, iv, v, i
Explanation
When the gene associated with enzyme synthesis is mutated, the enzyme becomes deficient, and as a result, the metabolic process becomes sluggish, and the substrate (substance) starts to accumulate in the cells. This results in storage disease.
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