Events associated with lysosomal disorders are mentioned below. Arrange them in a sequence with respect to their occurrence: i. Mutation ii. Storage diseases iii. Accumulation of substances within the cells iv. Deficiency of lysosomal enzymes v. Metabolic sluggishness
Correct answer: B. i, iv, v, iii, ii
- A. i, ii, iii, iv, v
- B. i, iv, v, iii, ii
- C. v, iv, iii, ii, i
- D. ii, iii, iv, v, i
Explanation
When the gene associated with enzyme synthesis is mutated, the enzyme becomes deficient, and as a result, the metabolic process becomes sluggish, and the substrate (substance) starts to accumulate in the cells. This results in storage disease.
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Animal, plant, prokaryotic and eukaryotic cells are compared through their membranes, cell walls, nuclei and cytoplasmic organelles. The work includes the structures and functions of mitochondria, chloroplasts, ribosomes, endoplasmic reticulum, Golgi apparatus and lysosomes, as well as chromosome organization and the distinction between chromatin and chromosomes.
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