Down's syndrome is a result of non-disjunction of_ pair of chromosomes that fails to segregate:
Correct answer: A. 21st
- A. 21st
- B. 22nd
- C. 18th
- D. 24th
Explanation
Down's syndrome, also known as trisomy 21, is a result of the non-disjunction of the 21st pair of chromosomes. In individuals with Down's syndrome, there is an extra copy of chromosome 21, leading to characteristic developmental and physical differences.
This question appeared on the UHS MDCAT 2013 paper, which you can sit online with every answer explained.
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About Chromosomes
Chromosomes are DNA-protein structures that carry genes and become visible during cell division. Coverage includes chromatin, centromeres, sister chromatids, homologous chromosomes, chromosome number, and the distinction between diploid and haploid cells, with links to DNA replication, mitosis and meiosis.
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