Chloramphenicol inhibits bacterial protein synthesis by binding primarily to which ribosomal subunit?
Correct answer: A. 50S subunit
- A. 50S subunit
- B. 40S subunit
- C. 30S subunit
- D. 60S subunit
Explanation
Chloramphenicol binds the 50S bacterial ribosomal subunit and inhibits peptidyl transferase activity. The 30S subunit is targeted by drugs such as tetracyclines and aminoglycosides.
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Covers how drugs act in animals, including pharmacokinetics, pharmacodynamics, routes of administration, dosage forms, adverse effects and drug interactions. Major groups include antimicrobials, antiparasitics, analgesics, anaesthetics, anti-inflammatory drugs, hormones and cardiovascular medicines, with attention to withdrawal periods and species differences.
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