Beta-lactam antibiotics generally show which type of antibacterial activity?

Correct answer: A. Time-dependent killing

  • A. Time-dependent killing
  • B. Concentration-dependent killing
  • C. Delayed receptor antagonism
  • D. Dose-independent killing

Explanation

The effectiveness of beta-lactams is mainly related to the time that free drug concentration remains above the pathogen's MIC. Increasing the peak concentration alone is less important than maintaining adequate exposure.

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Covers how drugs act in animals, including pharmacokinetics, pharmacodynamics, routes of administration, dosage forms, adverse effects and drug interactions. Major groups include antimicrobials, antiparasitics, analgesics, anaesthetics, anti-inflammatory drugs, hormones and cardiovascular medicines, with attention to withdrawal periods and species differences.

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