As the pH of the blood decreases, H+ ions increase, which combines with the protein part of hemoglobin, to decrease its ability to bind with:

Correct answer: A. O2

  • A. O2
  • B. CO2
  • C. CO
  • D. H2

Explanation

The Bohr effect describes hemoglobin's lower affinity for oxygen secondary to increases in the partial pressure of carbon dioxide and/or decreased blood pH. This lower affinity, in turn, enhances the unloading of oxygen into tissues to meet the oxygen demand of the tissue.

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