A patient with suspected ethylene glycol poisoning develops severe metabolic acidosis and increasing drowsiness. Which antidote is used to prevent formation of toxic metabolites?
Correct answer: A. Fomepizole
- A. Fomepizole
- B. Atropine
- C. Calcium gluconate
- D. Pralidoxime
Explanation
Fomepizole blocks alcohol dehydrogenase and limits production of toxic ethylene glycol metabolites. Atropine and pralidoxime treat cholinergic poisoning, while calcium gluconate is used for selected cardiac membrane problems such as hyperkalaemia.
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About Emergency Drugs and Antidotes
Emergency pharmacology covers drugs used in cardiac arrest, shock, severe allergy, acute asthma, seizures, poisoning and hypoglycaemia, including adrenaline, atropine, naloxone, flumazenil and selected antidotes. The focus is on indications, routes, rapid adverse effects, dose safety and matching a toxic substance with its specific reversal agent.
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