A patient who swallowed a large amount of aspirin has tinnitus, rapid breathing and a rising blood pH. Which treatment helps enhance salicylate elimination by alkalinising the urine?

Correct answer: A. Sodium bicarbonate

  • A. Sodium bicarbonate
  • B. Calcium gluconate
  • C. Naloxone
  • D. Atropine sulfate

Explanation

Intravenous sodium bicarbonate alkalinises serum and urine, increasing salicylate ionisation and renal elimination. It also requires monitoring of electrolytes, fluid status and acid base balance; naloxone and atropine do not treat salicylate poisoning.

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About Emergency Drugs and Antidotes

Emergency pharmacology covers drugs used in cardiac arrest, shock, severe allergy, acute asthma, seizures, poisoning and hypoglycaemia, including adrenaline, atropine, naloxone, flumazenil and selected antidotes. The focus is on indications, routes, rapid adverse effects, dose safety and matching a toxic substance with its specific reversal agent.

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