A patient develops seizures, metabolic acidosis and altered consciousness after ingesting a large amount of isoniazid. Which specific antidote should the nurse expect?
Correct answer: A. Pyridoxine
- A. Pyridoxine
- B. Folic acid
- C. Vitamin K
- D. Calcium gluconate
Explanation
Isoniazid toxicity is treated with pyridoxine, also called vitamin B6, because isoniazid depletes active pyridoxine and promotes seizures. Folic acid and vitamin K do not reverse isoniazid toxicity, and calcium gluconate is used for selected cardiac and electrolyte emergencies.
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About Emergency Drugs and Antidotes
Emergency pharmacology covers drugs used in cardiac arrest, shock, severe allergy, acute asthma, seizures, poisoning and hypoglycaemia, including adrenaline, atropine, naloxone, flumazenil and selected antidotes. The focus is on indications, routes, rapid adverse effects, dose safety and matching a toxic substance with its specific reversal agent.
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