A patient taking pioglitazone has gained 3 kg in two weeks and has increasing ankle swelling. Which finding should the nurse report first?
Correct answer: C. New ankle swelling with rapid weight gain
- A. Mild hunger before the evening meal
- B. A slight metallic taste after tablets
- C. New ankle swelling with rapid weight gain
- D. A blood glucose level within the prescribed target
Explanation
Pioglitazone can cause fluid retention and may worsen or precipitate heart failure. Rapid weight gain and peripheral oedema require prompt assessment, whereas the other findings are not the most urgent concern.
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About Endocrine and Diabetes Drugs
Endocrine pharmacology includes insulin preparations, oral antidiabetic drugs, thyroid and antithyroid medicines, corticosteroids, sex hormones and drugs affecting calcium balance. Questions address onset and duration, administration, monitoring, hypoglycaemia, steroid adverse effects and the difference between replacing a deficient hormone and suppressing excessive hormone activity.
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