A patient has started levothyroxine after treatment for primary hypothyroidism. Which laboratory test is used mainly to assess the adequacy of replacement?

Correct answer: A. Serum thyroid-stimulating hormone level

  • A. Serum thyroid-stimulating hormone level
  • B. Serum alanine aminotransferase level
  • C. Serum amylase level
  • D. Serum prothrombin time

Explanation

In primary hypothyroidism, thyroid-stimulating hormone is monitored to assess the response to levothyroxine replacement. The other tests assess liver function, pancreatic injury and coagulation rather than thyroid replacement.

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About Endocrine and Diabetes Drugs

Endocrine pharmacology includes insulin preparations, oral antidiabetic drugs, thyroid and antithyroid medicines, corticosteroids, sex hormones and drugs affecting calcium balance. Questions address onset and duration, administration, monitoring, hypoglycaemia, steroid adverse effects and the difference between replacing a deficient hormone and suppressing excessive hormone activity.

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