A patient taking acarbose asks why the medicine is taken with the first bite of each meal. Which explanation is correct?
Correct answer: A. It delays intestinal carbohydrate digestion
- A. It delays intestinal carbohydrate digestion
- B. It stimulates insulin release during fasting
- C. It replaces the body's missing thyroid hormone
- D. It prevents glucose formation in the liver
Explanation
Acarbose inhibits intestinal alpha-glucosidase enzymes and slows carbohydrate breakdown, reducing the rise in blood glucose after meals. It must be taken with the first bite because its action occurs in the intestine during carbohydrate digestion.
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About Endocrine and Diabetes Drugs
Endocrine pharmacology includes insulin preparations, oral antidiabetic drugs, thyroid and antithyroid medicines, corticosteroids, sex hormones and drugs affecting calcium balance. Questions address onset and duration, administration, monitoring, hypoglycaemia, steroid adverse effects and the difference between replacing a deficient hormone and suppressing excessive hormone activity.
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