Free Neurophysiology MCQs with Answers

64 Neurophysiology MCQs from Physiology, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.

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  • A. GABA
  • B. Glutamate
  • C. Aspartic acid
  • D. Lysin

Explanation: GABA is the principal inhibitory neurotransmitter in the brain, usually reducing neuronal excitability by increasing chloride or potassium…

Correct answer: GABA
  • A. Vagus nerve
  • B. Facial nerve
  • C. Trigeminal nerve
  • D. Glossopharyngeal nerve

Explanation: The afferent limb of the corneal reflex travels through the ophthalmic division of the trigeminal nerve, while the efferent blinking…

Correct answer: Trigeminal nerve
  • A. Reticulospinal
  • B. Vestibulospinal
  • C. Rubrospinal
  • D. Corticospinal

Explanation: The corticospinal tract is a pyramidal tract involved in voluntary skilled movement.

Correct answer: Corticospinal
  • A. Sympathetic nerves
  • B. Parasympathetic nerves
  • C. Sensory nerves
  • D. Motor nerves

Explanation: Sweat glands receive sympathetic autonomic fibres, but unlike most sympathetic postganglionic fibres, these release acetylcholine rather…

Correct answer: Sympathetic nerves
  • A. Deuteranopia
  • B. Protanopia
  • C. Protanomaly
  • D. Deuteranomaly

Explanation: Protanopia is absence of the red-sensitive L cone and causes red colour blindness.

Correct answer: Protanopia
  • A. Astrocytes
  • B. Schwann cells
  • C. Oligocytes
  • D. Microglia

Explanation: Microglia are the resident macrophage-like cells of the CNS, so they remove cellular debris and phagocytose pathogens.

Correct answer: Microglia
  • A. Neuronal inhibition
  • B. Neuronal activation
  • C. Glial cell inhibition
  • D. Glial cell activation

Explanation: GABA is the major inhibitory neurotransmitter in the CNS; it usually reduces neuronal excitability by increasing chloride entry or…

Correct answer: Neuronal inhibition
  • A. Motor areas of cerebral cortex
  • B. Basal ganglia complex
  • C. Pathways for recurrent collateral inhibition in the spinal cord
  • D. Anterior hypothalamus

Explanation: Chorea and athetosis are hyperkinetic movement disorders caused by dysfunction of the basal ganglia circuits, which normally help regulate…

Correct answer: Basal ganglia complex
  • A. Touch
  • B. Temperature
  • C. Muscle sense
  • D. Vibration sense

Explanation: A hemisection of the spinal cord causes ipsilateral loss of vibration, position and fine touch, while pain and temperature are lost on the…

Correct answer: Temperature
  • A. Schwan cell mitosis
  • B. Axonal sprouting
  • C. Nuclear disintegration
  • D. Myelin sheath degeneration

Explanation: After a nerve is cut, the distal axon and its myelin undergo Wallerian degeneration, with myelin breakdown occurring before Schwann-cell…

Correct answer: Myelin sheath degeneration
  • A. Nuclear bag intrafusal fibers
  • B. Nuclear chain
  • C. Golgi tendon organ
  • D. Pacinium corpuscles

Explanation: The primary endings of nuclear bag intrafusal fibres are especially sensitive to the rate of muscle stretch, producing the dynamic…

Correct answer: Nuclear bag intrafusal fibers
  • A. Disintegrating of Nucleus
  • B. Disappearance of nissel granules
  • C. Disintegration of golgi apparatus
  • D. Decrease in cell size

Explanation: Chromatolysis is the loss or dispersal of Nissl bodies in a neuron after axonal injury, accompanied by swelling of the cell body.

Correct answer: Disappearance of nissel granules
  • A. Schwann cells
  • B. Astrocytes
  • C. Oligodendrocytes
  • D. Microglia

Explanation: Oligodendrocytes form myelin around axons in the CNS, with one cell capable of myelinating segments of several axons.

Correct answer: Oligodendrocytes
  • A. Lateral walls
  • B. Nasal septum
  • C. Lateral wall and nasal septum above superior concha
  • D. None of the above

Explanation: Olfactory receptors lie in the olfactory epithelium at the roof of the nasal cavity, including the upper nasal septum and the lateral wall…

Correct answer: Lateral wall and nasal septum above superior concha
  • A. Midbrain
  • B. Hypothalamus
  • C. Cerebrum
  • D. Pons

Explanation: The hypothalamus is the major integrating centre for autonomic activity, linking visceral control with endocrine and behavioural…

Correct answer: Hypothalamus
  • A. Intrafusal fibers of the muscle spindle
  • B. Golgi tendon apparatus
  • C. Autoonomic preganglionic fibers
  • D. Spinothalamic tracts

Explanation: Group B fibres are small, myelinated fibres that include autonomic preganglionic axons.

Correct answer: Autoonomic preganglionic fibers
  • A. Medulla
  • B. Precentral gyrus
  • C. Diencephalon
  • D. Hypothalamus

Explanation: The hypothalamus maintains body temperature by comparing thermal input with a set point and activating heat-loss or heat-production…

Correct answer: Hypothalamus
  • A. Babinsky test
  • B. Weber's test
  • C. Finger - nose test
  • D. Chvostek test

Explanation: Weber's test uses a tuning fork placed on the midline of the skull to compare sound lateralisation and is useful for detecting conductive…

Correct answer: Weber's test
  • A. Trigeminal nerve ganglion
  • B. Otic ganglion
  • C. Geniculate ganglion
  • D. Superior cervical ganglion

Explanation: Taste fibres from the anterior two-thirds of the tongue travel with the chorda tympani branch of the facial nerve, whose sensory cell…

Correct answer: Geniculate ganglion
  • A. Temporal lobe
  • B. Stria nigra
  • C. Frontal lobe
  • D. Hypothalamus

Explanation: The hypothalamus contains feeding centres that regulate hunger and satiety, classically described as a lateral hunger centre and a…

Correct answer: Hypothalamus