All Free Oral Pathology and Medicine MCQs with Answers

• A. CD8
• B. CD4
• C. Monocytes
• D. Lymphocytes

Explanation: HIV primarily infects CD4-positive helper T lymphocytes through the CD4 receptor, causing progressive cellular immunodeficiency.

• A. Rubella
• B. Cytomegalovirus
• C. Measles
• D. Herpes simplex

Explanation: Rubella, cytomegalovirus, and herpes simplex virus can produce congenital fetal abnormalities, whereas measles is not classically listed…

• A. Hairy leukoplakia
• B. Erythroplakia
• C. Oral lichen planus
• D. Bullous pemphigoid

Explanation: Oral hairy leukoplakia is strongly associated with HIV-related immunosuppression and is caused by Epstein-Barr virus, typically affecting…

• A. cells of the surface epithelium
• B. Stromal connective tissue
• C. Nuclei of the striated muscle cells
• D. Cytoplasm of the striated muscle cells

Explanation: In lingual amyloidosis, amyloid accumulates mainly in the stromal connective tissue and around vessels, producing enlargement and firmness…

• A. Vitamin B deficiency
• B. Vitamin C deficiency
• C. Syphilis
• D. Iron deficiency

Explanation: Luetic glossitis is a manifestation of syphilis, particularly in later disease, and may cause atrophy, fissuring and loss of lingual…

• A. nicotinic acid
• B. thiamine
• C. Riboflavin
• D. pyridoxine

Explanation: A magenta or purplish-red tongue is a classic oral sign of riboflavin deficiency, often accompanied by cheilosis and angular fissures.

• A. Leprosy
• B. Syphilis
• C. Tuberculosis
• D. None of the above

Explanation: Primary amyloidosis is caused by deposition of immunoglobulin light-chain amyloid and is not secondary to infections such as tuberculosis…

• A. Melanoma
• B. Melasma
• C. Freckle
• D. Cafe-au-lait-spots

Explanation: Melasma is acquired, bilateral facial hyperpigmentation that is intensified by sunlight and associated with pregnancy or oral…

• A. Toxicity of silver
• B. Toxicity of lead
• C. Toxicity of Mercury
• D. Toxicity of Tetracycline

Explanation: Pink disease, or acrodynia, is a childhood manifestation of mercury poisoning and may include painful extremities, sweating, irritability…

• A. Addision's disease
• B. Peutz-Jeghers syndorme
• C. Hyper pituitarism
• D. Von recklinghausen disease

Explanation: Multiple café-au-lait macules are characteristic of neurofibromatosis type 1, also called von Recklinghausen disease.

• A. Erythroblastosis fetalis
• B. Fluorosis
• C. Tetracycline therapy Fluorosis
• D. None of the above

Explanation: Green intrinsic staining of teeth can result from bilirubin deposition during erythroblastosis fetalis, a haemolytic disease of the…

• A. Ulcerations of oral mucosa
• B. Sebaceous glands of oral mucosa
• C. None of the above
• D. Silver pigmentation of oral mucosa

Explanation: Peutz-Jeghers syndrome causes multiple mucocutaneous melanin macules, especially on the lips and buccal mucosa.

• A. Neuro fibromatosis
• B. fibrous dysplasia
• C. Addison's disease
• D. None of the above

Explanation: Neurofibromatosis may produce café-au-lait macules and other brownish pigmentation despite normal routine laboratory findings.

• A. Hyperthyroidsim
• B. addison's disease
• C. Nephritis
• D. All of the above

Explanation: Adrenal insufficiency in Addison disease increases melanocyte-stimulating hormone activity, producing diffuse skin and oral melanin…

• A. Epulis
• B. Melanoma
• C. Melasma
• D. Melanosis

Explanation: Pregnancy-related facial melanin hyperpigmentation is called melasma, also known as chloasma or the mask of pregnancy.

• A. Encephalitis
• B. GIT disturbances
• C. Peripheral neuritis
• D. Hallucinations

Explanation: Lead poisoning commonly causes gastrointestinal symptoms, peripheral neuropathy, and encephalopathy, particularly in severe exposure.

• A. Peutz-Jeghers syndrome
• B. Plummer-Vinson syndrome
• C. Lead poisoning
• D. Bechet's syndrome

Explanation: Peutz-Jeghers syndrome causes multiple mucocutaneous melanin macules, especially around the lips and oral cavity.

• A. Yellow and brown stains only in enamel
• B. Yellow and brown stains in enamel and dentin
• C. Yellow and brown stains only in dentin
• D. Only yellow stain in enamel

Explanation: Tetracycline binds calcium during tooth mineralisation, so it becomes incorporated into both enamel and dentin.

• A. High-protein diet
• B. Erythromycin
• C. penicillins
• D. Tetracyclines

Explanation: Tetracyclines cross the placenta and enter breast milk, and in children they bind calcium in developing teeth, causing intrinsic yellow…

• A. Haemosiderin
• B. Biliribin
• C. Methemoglobin
• D. Myoglobin

Explanation: Iron overload in haemochromatosis leads to deposition of haemosiderin, producing bronze or brown pigmentation of tissues.