Free Mendel's Laws of Inheritance MCQs with Answers

130 Mendel's Laws of Inheritance MCQs from Biology, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.

Mendelian inheritance explains how alleles separate into gametes and assort during reproduction, producing predictable genotype and phenotype ratios. Questions cover dominance, recessiveness, homozygous and heterozygous conditions, the laws of segregation and independent assortment, monohybrid and dihybrid crosses, test crosses and the limits caused by linked genes.

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130 questions · page 2 of 7

Moderate
  • A. two sister chromatids of the same chromosome
  • B. any two chromatids chosen at random
  • C. the two strands of one DNA molecule
  • D. non sister chromatids of homologous chromosomes

Explanation: Exchange between non sister chromatids of homologues shuffles maternal and paternal alleles, creating recombinant gametes.

Correct answer: non sister chromatids of homologous chromosomes
Fairly easy
  • A. chiasmata
  • B. centromeres
  • C. kinetochores
  • D. telomeres

Explanation: Chiasmata can be seen under the microscope in prophase one and mark where crossing over has occurred.

Correct answer: chiasmata
Fairly easy
  • A. micrometres
  • B. map units, or centiMorgans
  • C. nanometres
  • D. base pairs per gamete

Explanation: One map unit, one centiMorgan, equals one per cent recombination between two genes.

Correct answer: map units, or centiMorgans
  • A. no recombination at all
  • B. complete linkage in every meiosis
  • C. a higher recombination frequency than genes lying close together
  • D. fewer crossing overs than genes lying close together

Explanation: The longer the stretch of chromosome between two genes, the more likely a crossover will fall between them, so distant genes recombine…

Correct answer: a higher recombination frequency than genes lying close together
Moderate
  • A. Gregor Mendel
  • B. Jean Baptiste Lamarck
  • C. James Watson
  • D. Thomas Hunt Morgan

Explanation: Morgan showed that certain Drosophila characters were inherited together and tied to the sex chromosomes, founding chromosome mapping.

Correct answer: Thomas Hunt Morgan
Moderate
  • A. parental combinations of characters
  • B. equal numbers of all four combinations
  • C. recombinant combinations only
  • D. non viable zygotes

Explanation: Because linked genes usually travel together, parental combinations outnumber recombinants, and the size of the minority reveals how far…

Correct answer: parental combinations of characters
Very hard
  • A. 46
  • B. 23
  • C. 22
  • D. 44

Explanation: One linkage group corresponds to each kind of chromosome in the haploid set, so humans have 23.

Correct answer: 23
  • A. 25 per cent
  • B. 40 per cent
  • C. 50 per cent
  • D. 100 per cent

Explanation: Once genes are far enough apart that a crossover happens between them in every meiosis, half the gametes are recombinant, the same figure…

Correct answer: 50 per cent
  • A. autosomal
  • B. Y linked
  • C. mitochondrial
  • D. X linked

Explanation: The X chromosome carries many genes unrelated to sex, and their inheritance is distinctive because males have only one copy.

Correct answer: X linked
Fairly easy
  • A. has only one X chromosome
  • B. has two Y chromosomes
  • C. inactivates the normal allele
  • D. lacks the gene altogether

Explanation: With no second X to supply a dominant allele, the single recessive allele has nothing to mask it, a state called hemizygosity.

Correct answer: has only one X chromosome
  • A. None
  • B. Half
  • C. A quarter
  • D. All of them

Explanation: The woman must be a carrier since she inherited her affected father's X.

Correct answer: Half
Hard
  • A. was cured by royal physicians
  • B. is common in every royal family
  • C. was traced through the descendants of Queen Victoria
  • D. was first described by a king

Explanation: Victoria carried the allele and passed it into the royal houses of Russia and Spain, producing affected princes across Europe.

Correct answer: was traced through the descendants of Queen Victoria
Very hard
  • A. from mother to sons
  • B. from father to all his sons
  • C. equally to sons and daughters
  • D. to daughters only

Explanation: Only males carry a Y chromosome, and a father passes it to every son and no daughter, so Y linked traits run strictly down the male line.

Correct answer: to daughters only
Fairly easy
  • A. Red green colour blindness
  • B. Sickle cell anaemia
  • C. Down syndrome
  • D. Albinism

Explanation: The genes for red and green pigments lie on the X chromosome, so colour blindness follows the X linked pattern.

Correct answer: Red green colour blindness
Moderate
  • A. a man suffering from the disease
  • B. a heterozygous woman with one normal and one haemophilia allele
  • C. a homozygous normal woman
  • D. a person with an extra chromosome

Explanation: A carrier holds the recessive allele without symptoms because the normal allele on her other X is enough for clotting.

Correct answer: a heterozygous woman with one normal and one haemophilia allele
  • A. zero
  • B. one quarter
  • C. one half
  • D. certain

Explanation: The woman inherited her haemophiliac father's X, making her a carrier. She passes that X to half her sons, who will be affected, and the…

Correct answer: one half
Fairly easy
  • A. centromere
  • B. nucleolus
  • C. chiasma
  • D. Barr body

Explanation: The inactivated X, or Barr body, equalises the gene dose between XX females and XY males.

Correct answer: Barr body
Hard
  • A. Alleles separate during gamete formation
  • B. Different genes assort independently
  • C. Dominant alleles always mask recessive
  • D. Genes are on chromosomes

Explanation: The law of segregation states that allele pairs separate during gamete formation, so each gamete carries one allele.

Correct answer: Alleles separate during gamete formation
Fairly easy
  • A. Only dominant phenotype
  • B. Only recessive phenotype
  • C. Intermediate phenotype
  • D. Both phenotypes expressed

Explanation: In incomplete dominance, the heterozygote shows an intermediate phenotype, e.g., pink flowers from red and white parents.

Correct answer: Intermediate phenotype
Moderate
  • A. Heterozygote frequency
  • B. Homozygous dominant frequency
  • C. Homozygous recessive frequency
  • D. Total alleles

Explanation: p² = frequency of homozygous dominant (AA), 2pq = heterozygous (Aa), q² = homozygous recessive (aa).

Correct answer: Homozygous dominant frequency