Which toxin is responsible for the characteristic rigid paralysis of generalized tetanus in a horse?

Correct answer: A. Tetanospasmin from Clostridium tetani

  • A. Tetanospasmin from Clostridium tetani
  • B. Botulinum toxin from Clostridium botulinum
  • C. Endotoxin from Escherichia coli
  • D. Alpha toxin from Clostridium perfringens

Explanation

Tetanospasmin blocks inhibitory neurotransmission, producing muscle rigidity, spasms, and a locked jaw. Botulinum toxin causes flaccid paralysis, which is the important contrast in this question.

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