Which statement correctly describes the action of propylthiouracil in a patient with hyperthyroidism?
Correct answer: A. It reduces thyroid hormone synthesis and peripheral conversion of thyroxine
- A. It reduces thyroid hormone synthesis and peripheral conversion of thyroxine
- B. It replaces deficient thyroid hormone and raises the metabolic rate
- C. It destroys thyroid tissue by delivering radioactive iodine
- D. It blocks calcium absorption and lowers the serum calcium level
Explanation
Propylthiouracil inhibits thyroid hormone synthesis and also reduces peripheral conversion of thyroxine to triiodothyronine. Levothyroxine replaces hormone, radioactive iodine ablates thyroid tissue, and calcium absorption is unrelated to its main action.
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About Endocrine and Diabetes Drugs
Endocrine pharmacology includes insulin preparations, oral antidiabetic drugs, thyroid and antithyroid medicines, corticosteroids, sex hormones and drugs affecting calcium balance. Questions address onset and duration, administration, monitoring, hypoglycaemia, steroid adverse effects and the difference between replacing a deficient hormone and suppressing excessive hormone activity.
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