A patient with type 2 diabetes takes metformin. Which laboratory assessment is most important for ongoing safety?
Correct answer: A. Serum creatinine and estimated glomerular filtration rate
- A. Serum creatinine and estimated glomerular filtration rate
- B. Serum amylase and lipase levels
- C. Total bilirubin and alkaline phosphatase
- D. Haemoglobin and platelet count
Explanation
Metformin is cleared mainly by the kidneys, so renal function must be assessed before and during treatment. Reduced renal clearance increases the risk of drug accumulation and lactic acidosis.
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About Endocrine and Diabetes Drugs
Endocrine pharmacology includes insulin preparations, oral antidiabetic drugs, thyroid and antithyroid medicines, corticosteroids, sex hormones and drugs affecting calcium balance. Questions address onset and duration, administration, monitoring, hypoglycaemia, steroid adverse effects and the difference between replacing a deficient hormone and suppressing excessive hormone activity.
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50 free Endocrine and Diabetes Drugs MCQs from Nursing Pharmacology, each with the correct answer and an explanation. Unlimited attempts, no account needed.
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