Which statement about the active site of an enzyme is correct?
Correct answer: B. It is a small region whose shape and charges complement the substrate
- A. It occupies most of the enzyme's surface
- B. It is a small region whose shape and charges complement the substrate
- C. It binds any molecule of similar mass
- D. It is destroyed after each reaction
Explanation
Only a few residues, often far apart in the primary sequence but brought together by folding, form the active site, which is why the whole three dimensional structure matters. Complementarity of shape and charge is what produces specificity. The site is regenerated after each catalytic cycle.
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About Enzymes as Biocatalysts
Enzymes are protein or RNA biocatalysts that lower activation energy without being consumed, and their active sites bind specific substrates. The topic covers the lock and key and induced fit models, effects of temperature, pH and substrate concentration, cofactors, enzyme specificity, and competitive versus non-competitive inhibition.
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