Asked in NUMS 2022 2022Moderate

Which option is correct about non-competitive inhibition

Correct answer: B. Enzyme shape distorted

  • A. Malonate act as inhibitor
  • B. Enzyme shape distorted
  • C. Competition for active site
  • D. Inactive enzyme gettlng reactivated

Explanation

A noncompetitive inhibitor binds to the enzyme away from the active site, altering the shape of the enzyme so that even if the substrate can bind, the active site functions less effectively.

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About Enzyme Inhibitors

Enzyme inhibitors reduce reaction rate by interfering with enzyme-substrate interaction or catalytic activity. Coverage includes reversible competitive, non-competitive and uncompetitive inhibition, the effects of inhibitor concentration on reaction rate, and why competitive inhibition can be reduced by increasing substrate concentration.

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