In enzymatic activity, the term "feedback inhibition" is used when:

Correct answer: A. Enzyme is inhibited by the product being produced

  • A. Enzyme is inhibited by the product being produced
  • B. Enzyme works normally for regulatory mechanism
  • C. Enzyme remains unaffected by product concentration
  • D. Enzyme is inhibited irreversibly

Explanation

Feedback regulation of an enzyme occurs when a product of the reaction binds to an allosteric site on the enzyme and affects its catalytic activity. This results in an reversible inhibition of enzyme.

This question appeared on the NUMS 2021 paper, which you can sit online with every answer explained.

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About Enzyme Inhibitors

Enzyme inhibitors reduce reaction rate by interfering with enzyme-substrate interaction or catalytic activity. Coverage includes reversible competitive, non-competitive and uncompetitive inhibition, the effects of inhibitor concentration on reaction rate, and why competitive inhibition can be reduced by increasing substrate concentration.

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