Which of the following most appropriately describes haemophilia?
Correct answer: D. X-linked recessive gene disorder
- A. Chromosomal disorder
- B. Dominant gene disorder
- C. Recessive gene disorder
- D. X-linked recessive gene disorder
Explanation
Hemophilias (e.g, factor VIII/IX defects) are caused by mutations on the X chromosome and show recessive inheritance - classic X-linked recessive.
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About Inheritance
Mendel's laws explain segregation, independent assortment and the prediction of genetic ratios using alleles, genotypes and phenotypes. The chapter also covers linked genes, recombination and crossing over during meiosis, then applies pedigree reasoning to X-linked recessive traits, which show different inheritance patterns in males and females.
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