Which of the following is related to an enzyme deficiency and involves periodontal destruction around primary teeth______________?
Correct answer: A. Hypophosphatasia
- A. Hypophosphatasia
- B. Cyclic neutropenia
- C. Juvenile Periodontitis
- D. Papillion Lefevre syndrome
Explanation
Hypophosphatasia is caused by deficiency of tissue-nonspecific alkaline phosphatase, impairing mineralization and causing premature loss of primary teeth with periodontal destruction. Papillon-Lefèvre syndrome also causes early periodontal destruction, but it is related to cathepsin C deficiency and characteristic palmoplantar keratosis.
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